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This medication is utilized to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing oil that is facialsebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.

OTHER USES: This part contains uses of this drug that are not detailed in the approved professional labeling for the drug but which will be prescribed by your wellbeing care expert. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This medicine can also be used to treat a type that is certain of (neuroblastoma).

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Read the Medication Guide provided by your pharmacist you get a refill before you start using isotretinoin and each time. Read and sign a Patient Information/Informed Consent form before you start taking this medication. If you have any relevant questions about isotretinoin, consult with your medical practitioner or pharmacist before taking the medication.

Swallow capsules whole. Don't crush or chew them. Isotretinoin is often taken twice daily for 15-20 weeks, or as directed by your physician. Directions for most generic forms of isotretinoin state that it should really be taken with dishes. Nonetheless, the FDA has indicated that the Absorica brand might be taken with or without food. Food helps increase absorption of this drug into your bloodstream. Ask your doctor or pharmacist to get more information. Take this drug with a glass that is full of, and do not lie down for 10 mins after taking it.

The dosage is based on your medical condition, weight, and response to treatment.

Your acne may worsen through the first day or two of using this medication, also it may take up to 1-2 months before you notice the full benefit of this medication. A second course of treatment may be started after you have stopped taking the drug for 2 months if severe acne returns. The manufacturer will not suggest use that is long-term of. Don't take more than the recommended dose.

Since this drug may be consumed through the skin and lung area and may damage an baby that is unborn ladies who are pregnant or who can become pregnant should perhaps not manage this medication or inhale the dust from the capsules.

Negative Effects

Dry lips and mouth, minor swelling of the eyelids or lips, crusty skin, nosebleeds, upset stomach, or thinning of hair may take place. If some of these effects persist or aggravate, tell your pharmacist or doctor promptly.

To relieve mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or utilize a saliva substitute.

Remember that the doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of side effects because he or. Many people using this medication do not have serious adverse effects.

Tell your doctor right away in the event that you have some of these not likely but side that is serious: mental/mood changes (e.g., depression, aggressive or violent behavior, plus in uncommon instances, thoughts of committing suicide), tingling feeling in the skin, quick/severe sunburn (sunlight sensitiveness), back/joint/muscle discomfort, signs of disease (age.g., fever, persistent sore throat), painful swallowing, peeling epidermis on palms/soles.

Isotretinoin may rarely cause disease regarding the pancreas (pancreatitis) that may hardly ever be fatal. Stop taking this medication and inform your medical practitioner immediately if you develop: severe stomach pain, severe or persistent nausea/vomiting.

Stop taking this medication and tell your doctor appropriate away if you develop these unlikely but very serious side-effects: severe hassle, eyesight changes, ringing in the ears, hearing loss, chest pain, yellowing eyes/skin, dark urine, severe diarrhea, anal bleeding.

A very severe allergic reaction to this drug is rare. However, seek immediate attention that is medical you notice any observeable symptoms of a critical allergic effect, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing.

This isn't a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

Into the US -

Phone your physician for medical advice about side effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Phone your medical professional for medical advice about adverse effects. You may possibly report effects that are side Health Canada at 1-866-234-2345.


Before taking isotretinoin, tell your doctor or pharmacist if you have any other allergies if you are allergic to it; or to vitamin A-related drugs (other retinoids such as tretinoin); or. This product may contain inactive ingredients (such as soybean, parabens), which can cause allergy symptoms or other problems. Some people who are sensitive to peanuts may be allergic to also soy. Confer with your pharmacist for more details.

Anorexia nervosa), alcohol abuse, pancreatitis, bone loss conditions (e.g., osteoporosis/osteomalacia, decreased bone density) before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, family or personal history of high blood fats (triglycerides), family or personal history of psychiatric disorders (including depression), liver disease, obesity, eating disorders ( e.g..

Do not donate bloodstream after you stop taking it while you are taking isotretinoin and for at least 1 month.

This medicine may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear clothing that is protective out-of-doors.

Isotretinoin make a difference your vision night. Do not drive, use machinery, or do any activity that requires clear vision after dark until you are sure you can perform such activities safely.

If you wear contact lenses, you may not tolerate them as well as usual while using this medication. Contact your medical practitioner for more information.

Would not have procedures that are cosmetic smooth your skin (e.g., waxing, laser, dermabrasion) during and for 6 months after isotretinoin therapy. Skin scarring might occur.

Avoid the use of alcohol while taking this medication because it might increase the risk of certain unwanted effects (e.g., pancreatitis).

Limited information shows isotretinoin might cause some bone loss effects. Therefore, playing contact or repetitive impact sports (e.g., football, basketball, soccer, tennis) may result in bone problems, including an increased risk of broken bones. Limited information also suggests isotretinoin may stop normal growth in some children (epiphyseal plate closure). Check with your physician for more details.

Care is recommended when making use of this medication within the elderly because they might be more sensitive to its effects, especially the impacts on bones.

Caution is advised when using this drug in kids because they may be more responsive to its results, specially back/joint/muscle pain.

This drug ought not to be utilized during pregnancy or by those who may become pregnant during treatment. If you become pregnant or think you may be pregnant, inform your doctor right away. See section that is also warning.

Since this drug could be absorbed through skin and lungs and may harm an unborn baby, females who're pregnant or who may become pregnant must not handle this medication or breathe the dust from the capsules.

You must have two pregnancy that is negative before starting this medication. You must have a monthly pregnancy test during treatment with isotretinoin. If the test is good, you must stop taking this medication and check with your doctor appropriate away.

It's unknown if this medication passes into breast milk. Nonetheless, similar drugs pass into breast milk. Breast-feeding while by using this drug is not recommended. Consult your medical practitioner before breast-feeding.

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