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Clomipramine is used to treat obsessive disorder that is compulsiveOCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform duplicated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living.

This medication belongs to a course of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, and others) in the mind.

DIFFERENT USES: This area contains uses of the drug which can be perhaps not placed in the approved professional labeling for the drug but that may be prescribed by the medical care professional. Utilize this drug for a condition that is detailed in this section only if it was so prescribed by your health care professional.

This medication has additionally been utilized to treat depression, panic assaults, and ongoing pain.

How to use Anafranil

Read the Medication Guide available from your own pharmacist. Check with your pharmacist or doctor if you have any concerns.

Take this medication by mouth with or without meals as directed by your physician. To reduce side effects such as stomach upset, clomipramine may be started at a low dose, given in several doses during the day with meals, and slowly increased as your body gets used to it. After you have reached the best dose for you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor. Frequently, the dose that is daily not be more than 250 milligrams for grownups and 200 milligrams for young ones and teenagers.

Follow your doctor's instructions very carefully. Never just take more or less medication or frequently take it more than prescribed. Your condition shall not improve any faster and your threat of adverse results such as for example seizures may be increased. Dosage is based on your medical condition and response to therapy.

Avoid eating drinking or grapefruit grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your pharmacist or doctor for more details.

Make use of this medication regularly in order to have the most benefit from it. Continue to take it even if you feel well. To help you remember, use it at the time( that is same) each time.

Never suddenly stop using this medication without consulting your physician. Some conditions may become worse when the drug is suddenly stopped. You'll experience sweating, dizziness, nausea, vomiting, headache, or irritability if you suddenly stop taking this drug. Your dose may need to be gradually decreased.

It might take 2 to 3 weeks or longer prior to the full effects of this medication are noticed. Inform your doctor if your condition persists or if it worsens.

Side Effects

See also Warning section.

Dizziness, drowsiness, dry lips, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety signs may temporarily worsen when you first start clomipramine that is taking. If any of these effects persist or worsen, notify your doctor or pharmacist quickly.

To relieve mouth that is dry suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or use a saliva substitute.

To stop constipation, maintain a meal plan sufficient in fiber, drink plenty of water, and exercise. If you then become constipated while by using this drug, check with your pharmacist for help in selecting a laxative (age.g., stimulant-type with stool softener).

Understand that your medical practitioner has recommended this medication because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have adverse that is serious.

Tell your physician right away if any of these unlikely but side that is serious happen: mental/mood changes (e.g., confusion, despair, memory problems), enlarged/painful breasts, unwanted breast milk production, irregular/painful menstrual periods, muscle stiffness, ringing in the ears, sexual issues (e.g., decreased sexual ability, changes in desire), shakiness (tremors), numbness/tingling for the hands/feet, trouble urinating.

Tell your doctor right away if any of these rare but really serious side effects occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), unusual/uncontrolled motions (especially for the tongue/face/lips), serious stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and seldom cause an extremely serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away in the event that you develop a number of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, uncommon agitation/restlessness.

Get help that is medical away in the event that you have any very serious part effects, including: black stools, upper body pain, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, vision changes (such as seeing rainbows around lights during the night).

A very serious reaction that is allergic this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing.

This is simply not a list that is complete of adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Phone your physician for medical advice about side effects. You may report effects that are side FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side-effects. You may report effects that are side Health Canada at 1-866-234-2345.


Before taking clomipramine, tell your medical practitioner or pharmacist if you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or. This product may contain inactive ingredients, which can cause allergy symptoms or other dilemmas. Speak to your pharmacist for more information.

Before by using this medicine, tell your doctor or pharmacist your medical background, especially of: blood dilemmas (e.g., purpura, thrombocytopenia), breathing problems (age.g., asthma, chronic bronchitis), personal or genealogy and family history of glaucoma (angle-closure type), eating disorders (age.g., bulimia), heart dilemmas (e.g., arrhythmias, coronary artery disease, recent heart attack), intestinal problems (e.g., chronic constipation, ileus), liver problems, renal dilemmas, personal or genealogy of other mental/mood conditions (e.g., bipolar disorder, schizophrenia), history of hospitalization for a very serious reaction to certain medicines (neuroleptic malignant problem), heartburn/stomach acid in the esophagus (age.g., due to hiatal hernia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (urinary retention, enlarged prostate), any condition that may raise your danger of seizures (e.g., alcohol/sedative dependency, utilization of electroconvulsive treatment, mind injury/disease), specific kinds of tumors (e.g., pheochromocytoma, neuroblastoma).

Clomipramine may cause an ailment that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause severe (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that want medical help straight away.

The danger of QT prolongation are increased if you have actually certain medical conditions or are using other drugs that may cause QT prolongation. Before using clomipramine, inform your medical professional or pharmacist of all drugs you take and when you have any one of the following conditions: certain heart disease (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may increase your risk also of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about making use of clomipramine safely.

This drug will make you dizzy or drowsy or cause temporary vision that is blurred. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

To decrease dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

Before having surgery, tell your doctor or dentist that you're taking this medication.

Care is recommended when working with this drug in kids who participate in active recreations because it might increase the possibility of heart problems. (See also the Warning section.)

Older grownups may be more delicate to the relative unwanted effects of this drug, especially bleeding, confusion, dizziness, and QT prolongation (see above).

This medication should be used only when clearly needed during pregnancy. Newborns exposed to clomipramine during pregnancy may experience withdrawal symptoms or negative effects. Inform your doctor right away if you notice jitteriness, shaking, feeding problems, fast breathing, or seizures in your newborn.

Since untreated mental/mood problems (such as for instance obsessive disorder that is compulsive depression, panic attack) can be a serious condition, do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.

This medication passes into breast milk and may have effects that are undesirable a nursing baby. Consult your doctor before breast-feeding.

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