This medication is used to stop or treat gout attacks (flares). Usually gout signs develop unexpectedly and involve just one or a joints that are few. The big toe, knee, or ankle joints are most often affected. Gout is caused by too much uric acid in the blood. When acid that is uric within the blood are way too high, the uric acid may form hard crystals in your joints. Colchicine functions by decreasing swelling and lessening the create up of the crystals crystals that cause pain within the affected joint(s).
This medication is also utilized to prevent attacks of pain in the abdomen, chest, or joints caused by a particular inherited disease (familial Mediterranean fever). It really is thought to operate by decreasing your production of a protein that is certain A) that builds up in people with familial Mediterranean fever.
Colchicine is not a discomfort medication and should perhaps not be used to relieve other reasons for discomfort.
OTHER USES: This area contains uses of this drug that aren't detailed in the approved labeling that is professional the drug but which may be recommended by the health care professional. Use this medication for a condition that is detailed in this part only if it happens to be so recommended by your quality of life care professional.
This medication may also be used to reduce swelling and inflammation of this sac that covers the surface of the heart, a condition called pericarditis.
Read the Medication Guide provided by your pharmacist you get a refill before you start taking colchicine and each time. If you have any relevant concerns concerning the information, ask your medical practitioner or pharmacist.
Just take this medication by mouth with or without food, exactly as directed by your doctor. Dosing recommendations vary widely and may be different from the recommendations that are following. Taking more than the recommended dose might maybe not increase this drug's effectiveness and could increase your risk for negative effects. Ask your pharmacist or doctor for more details.
If you're taking this medicine to treat a gout attack, carefully follow the directions given by your doctor. This medication works best if you take it at the first sign of an attack. The suggested dose is 1.2 milligrams at the sign that is first of attack, followed by 0.6 milligrams one hour later. The maximum recommended dose is 1.8 milligrams taken over a 1-hour period. Ask your physician ahead of time about how soon you can repeat treatment with this medicine if another gout is had by you attack.
If you are taking this medication to prevent gout attacks or for pericarditis, ask your doctor about the dose and schedule you should follow. Very carefully follow your doctor's directions.
The usual dose is 1.2 to 2.4 milligrams daily if you are taking this medication to prevent attacks of pain caused by familial Mediterranean fever. The total dose may be taken as soon as daily or divided into two doses a day. Your physician might need to adjust your dose to control your symptoms or for those who have unwanted effects.
The dosage is dependant on your condition that is medical drugs/foods you may be taking, and response to treatment. To reduce your risk for serious adverse effects, do not increase your dose, take it more frequently, and take it for a significantly longer time than directed by the medical practitioner. Serious adverse effects may take place even at usual doses that are prescribed.
In the event your physician directs one to simply take colchicine regularly, use it frequently to get the most benefit from it. To help you remember, take it at the time( that is same) each day.
Avoid eating drinking or grapefruit grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.
If it worsens if you are taking this medication to treat symptoms due to familial Mediterranean fever, tell your doctor if your condition does not improve or.
Diarrhea, nausea, cramping, abdominal pain, and vomiting may occur. If any of these effects persist or worsen, tell your pharmacist or doctor promptly.
Remember that your doctor has prescribed this medication she has judged that the benefit to you is greater than the risk of adverse effects because he or. Many people using this medication do not have serious adverse effects.
Stop taking this medication and get help that is medical away if any of these extremely severe negative effects happen: unusual bleeding/bruising, serious diarrhea or vomiting, muscle tissue weakness or pain, numbness/tingling in your fingers or toes, pale or grey color of this lips/tongue/palms of fingers, indications of infection (such as for instance temperature, persistent sore throat), unusual weakness/tiredness, fast heartbeat, shortness of breath, change in the amount of urine.
A very serious allergic reaction to this drug is rare. However, seek immediate attention that is medical you see any symptoms of a significant allergic attack, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This isn't a list that is complete of side effects. If you notice other effects not listed above, contact your pharmacist or doctor.
In the usa -
Phone your doctor for medical advice about side-effects. You may possibly report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Phone your doctor for medical advice about side effects. You'll report side effects to wellness Canada at 1-866-234-2345.
Before using this medicine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic responses or other problems. Keep in touch with your pharmacist for more information.
Before using this medication, tell your physician or pharmacist your history that is medical of: renal problems, liver dilemmas (such as cirrhosis).
Alcohol can decrease this drug's effectiveness. Limit liquor while taking this drug.
This medicine can impact how well your body absorbs some meals and nutrients (such as for example vitamin B12). Consult your pharmacist or doctor to get more details.
Before having surgery, tell your doctor or dental practitioner about all the products you employ (including prescription drugs, nonprescription drugs, and herbal items).
Older grownups may be more sensitive to the relative negative effects of this medication, especially muscle mass weakness/pain and numbness/tingling in their fingers or toes.
Colchicine can decrease production that is sperm that might affect the power of a male to father a youngster. Consult with your medical practitioner for more information.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits together with your doctor.
This medicine passes into breast milk. While there were no reports of harm to nursing infants, consult your doctor before breast-feeding. Your doctor may recommend you take your medication apart from breast-feeding that you separate the time(s.
Airmail: 2-3 business weeks, EMS: 3-8 business days.
Airmail: 2-3 business weeks, EMS: 3-8 business days.