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This medication is used to treat problems that are mental/mood as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, help you sleep better, and increase your time level. This medicine belongs to a class of medicines called tricyclic antidepressants. It works by affecting the balance of certain chemicals that are naturalneurotransmitters such as for instance serotonin) in the brain.

OTHER USES: This section contains uses with this medication that are not listed in the approved labeling that is professional the drug but that could be prescribed by your quality of life care expert. Use this drug for a condition that is listed in this section only if it's been so recommended by the medical care professional.

This medication might also be employed to treat neurological discomfort (such as peripheral neuropathy, postherpetic neuralgia), eating disorder (bulimia), other mental/mood problems (such as anxiety, panic disorder), or to avoid migraine headaches.

Just how to use Endep

Read the drugs Guide provided by your pharmacist you get a refill before you start taking amitriptyline and each time. If you have any relevant concerns, check with your doctor or pharmacist.

Take this medicine by mouth, often 1 to 4 times daily or as directed by your physician. If you take it only once a day, take it at bedtime to help reduce daytime sleepiness. The dosage is based on your condition that is medical and to treatment.

To reduce your threat of adverse impacts (such as for instance drowsiness, dry lips, dizziness), your doctor may direct you to start this medication at a low dose and slowly increase your dose. Follow your medical practitioner's instructions very carefully.

Take this medication regularly to be able to obtain the benefit that is most from it. To help you remember, take it at the same time(s) each day. Do not increase your dose or use this drug more frequently or for longer than recommended. Your trouble will not improve any faster, and your threat of side results will increase.

It is vital to continue using this medication even if you feel well. Do not stop taking this medication without consulting your doctor. Some conditions may become worse whenever this drug is instantly stopped. Also, you might experience symptoms such as mood swings, headache, tiredness, and sleep change. To prevent these symptoms while you are stopping treatment with this drug, your doctor may reduce your dose gradually. Consult your pharmacist or doctor for more details. Report any new or symptoms that are worsening away.

This medicine may not work right away. You may see some benefit within a week. However, it may take up to 4 weeks before you feel the full effect.

Inform your medical professional if your condition persists or worsens (such as your feelings of sadness get worse, or perhaps you have thoughts of suicide).

Part Results

See also Warning section.

Drowsiness, dizziness, dry mouth, blurred vision, constipation, weight gain, or trouble urinating may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

To reduce the danger of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

To relieve dry mouth, suck on (sugarless) difficult candy or ice chips, chew (sugarless) gum, take in water, or make use of a saliva substitute.

To prevent constipation, keep a diet adequate in fiber, beverage plenty of water, and exercise. In the event that you become constipated while making use of this drug, consult your pharmacist for help in selecting a laxative.

Keep in mind that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of adverse effects. Many people using this medication do not have adverse that is serious.

Tell your doctor right away if any of those rare but serious side effects occur: easy bruising/bleeding, persistent heartburn, shaking, mask-like facial expressions, muscle spasms, severe stomach/abdominal discomfort, decreased sexual ability/desire, enlarged/painful breasts.

Get medical help right away in the event that you have any very serious side effects, including: black stools, vomit that seems like coffee grounds, serious dizziness, fainting, seizures, eye pain/swelling/redness, eyesight changes (such as seeing rainbows around lights at night).

This medication may rarely cause a very condition that is serious neuroleptic cancerous syndrome (NMS). Get medical help straight away when you yourself have any of the following signs: temperature, muscle mass stiffness, severe confusion, sweating, fast/irregular heartbeat.

A very serious reaction that is allergic this drug is rare. However, seek immediate medical attention if you notice any symptoms of a significant hypersensitive reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing.

That is maybe not a complete list of possible adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Into the US -

Phone your doctor for medical advice about adverse effects. You may report adverse effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.


See section that is also warning.

Before using amitriptyline, tell your medical practitioner or pharmacist if you have any other allergies if you are allergic to it, or to other tricyclic antidepressants (such as nortriptyline), or. This product may contain ingredients that are inactive which can cause allergies or other issues. Talk to your pharmacist for lots more details.

Before applying this medicine, tell your physician or pharmacist your medical history, especially of: bleeding problems, breathing problems, liver problems, recent heart assault, problems urinating (such as because of enlarged prostate), overactive thyroid (hyperthyroidism), personal or genealogy and family history of glaucoma (angle-closure type), personal or genealogy and family history of mental/mood conditions (such as bipolar disorder, psychosis), household history of suicide, seizures, conditions that may increase your threat of seizures (such as other brain disease, alcohol withdrawal).

Amitriptyline may cause a disorder that affects one's heart rhythm (QT prolongation). QT prolongation can hardly ever cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require medical attention immediately.

The risk of QT prolongation could be increased if you have specific conditions that are medical are taking other drugs that may cause QT prolongation. Before utilizing amitriptyline, tell your doctor or pharmacist of all the drugs you take and in the event that you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family members history of certain heart related illnesses (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you have conditions such as severe sweating, diarrhea, or vomiting if you use certain drugs (such as diuretics/"water pills") or. Confer with your doctor about using amitriptyline properly.

This drug may make you drowsy or dizzy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid beverages that are alcoholic.

Before having surgery, tell your doctor or dental practitioner about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outside.

If you have diabetes, this drug may make it harder to control your blood sugar levels. Monitor your blood sugar levels regularly and tell your doctor of the results. Your doctor may require to adjust your diabetes medication, exercise program, or diet.

Older grownups may be more sensitive to the negative effects with this medication, specially dry mouth, dizziness, drowsiness, confusion, constipation, difficulty urinating, and QT prolongation (see above). Dizziness, drowsiness, and confusion can boost the danger of dropping.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your medical practitioner.

Since untreated mental/mood issues (such as for example depression, anxiety, panic disorder) can be a serious condition, do not stop using this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.

This medication passes into breast milk and the result on a nursing infant is unknown. Consult your doctor before breast-feeding.

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