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This medication is utilized to deal with despair. It is also used with other therapies for the treating nighttime bed-wetting (enuresis) in kiddies. Using this medicine to deal with depression might boost your mood, sleep, appetite, and vitality and might help restore your curiosity about daily living. Imipramine might help your youngster control nighttime bed-wetting.

Imipramine belongs to a class of medicines called antidepressants that are tricyclic. It works by restoring the balance of certain natural substances (neurotransmitters such as norepinephrine) within the brain. For bed-wetting, this medicine may work by blocking the impact of a specific natural substance (acetylcholine) on the bladder.

DIFFERENT USES: This section contains uses of this drug that aren't detailed in the approved professional labeling for the drug but which may be prescribed by your wellbeing care pro. Utilize this drug for a condition that is listed in this section only if it has been so prescribed by the health care professional.

This medication may be used for also the treating anxiety and panic disorders.

Just how to utilize Tofranil

Read the Medication Guide available from your own pharmacist. Consult your pharmacist or doctor when you have any questions.

Take this medication by lips with or without food, frequently 1-4 times daily or as directed by the medical practitioner. You to take the entire dose once daily at bedtime if you have daytime drowsiness, your doctor may direct. Dosage is based on your medical condition and response to therapy. In children, dosage may also be based on body weight. To reduce your risk of side effects, your doctor may start you at a dose that is low gradually boost your dosage.

When used in children for bed-wetting, imipramine must be taken one hour before bedtime. If your child usually wets the bed early in the night, the drug may be given earlier in separate doses (e.g., one dose in the afternoon and one dose at bedtime).

Follow your physician's instructions very carefully. Do not take more or less medication or frequently take it more than prescribed. Your condition will not improve any faster and your threat of part results will increase. Utilize this medicine regularly so that you can have the most benefit from it. To help you remember, use it at the same time(s) each time.

This medication does not work right away. It may take up to 3 weeks if you are taking this medication for depression before you experience the full benefits.

It is important to continue taking this medication even in the event you feel good. Never abruptly stop using this medication without consulting your doctor. Some conditions may be worse once the drug is abruptly stopped. Your dosage may need to be gradually decreased.

When used for an excessive period in kids for bed-wetting, this medication may not work as well and might require different dosing. Talk with a doctor if this medication prevents working well.

Inform your doctor if the condition persists or worsens.

Negative Effects

Dry mouth, blurred vision, headache, drowsiness, dizziness, constipation, sickness, vomiting, loss of appetite, diarrhea, stomach cramps, fat gain/loss, and increased sweating might occur. If any of these effects persist or worsen, notify your doctor or pharmacist immediately.

Keep in mind that your doctor has prescribed this medicine she has judged that the benefit to you is greater than the risk of adverse effects because he or. Many people using this medication do not have serious side effects.

Tell your medical practitioner immediately if any of these unlikely but serious adverse effects occur: mental/mood changes (e.g., confusion, despair, memory problems), enlarged/painful breasts, unusual breast milk production, irregular/painful menstrual durations, muscle stiffness, restlessness, ringing ears, sexual dilemmas (e.g., decreased sexual ability, changes in desire), shakiness (tremors), numbness/tingling of the hands/feet, pain/redness/swelling of hands or feet, trouble urinating.

Inform your doctor appropriate away if any of the uncommon but extremely side that is serious occur: easy bruising/bleeding, signs of infection (e.g., fever, persistent sore throat), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, serious dizziness, serious nausea/vomiting/diarrhea, twitching muscles, unexplained fever, uncommon agitation/restlessness.

Get help that is medical away when you yourself have any very serious side impacts, including: chest pain, slow/fast/irregular heartbeat, fainting, seizures, slurred message, weakness on one side associated with human body, attention pain/swelling/redness, vision changes (such as seeing rainbows around lights at night).

An extremely severe allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble respiration.

This isn't a complete list of possible side effects. If you notice other effects not listed above, contact your pharmacist or doctor.

In the US -

Call your physician for medical advice about negative effects. You may report effects that are side Food And Drug Administration at 1-800-FDA-1088 or at

In Canada - Call your doctor for medical advice about side effects. You may report effects that are side Health Canada at 1-866-234-2345.


Before taking this medication, tell your doctor or pharmacist in the event that you have any other allergies if you are allergic to it; or to other tricyclic antidepressants (such as desipramine, amitriptyline); or. This product may contain inactive ingredients, that may cause allergies or other problems. Talk to your pharmacist to get more details.

This medication must not be used if you have a specific medical condition. Before using this medicine, consult your doctor or pharmacist if you have had: a heart attack that is recent.

Before applying this medication, tell your doctor or pharmacist your medical background, particularly of: difficulty in breathing (e.g., asthma, chronic bronchitis), individual or genealogy and family history of glaucoma (angle-closure type), diabetes, eating disorders (e.g., bulimia), heart dilemmas (e.g., arrhythmias, coronary artery disease), liver problems, kidney dilemmas, personal or family history of other mental/mood conditions (e.g., bipolar disorder, schizophrenia), seizures, overactive thyroid (hyperthyroidism), trouble urinating (age.g., due to enlarged prostate), any condition that may boost your risk of seizures (age.g., alcohol/sedative dependency, utilization of electroconvulsive therapy, mind injury/disease like stroke), specific kinds of tumors (e.g., pheochromocytoma, neuroblastoma).

Imipramine may cause a state of being which affects one's heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat along with other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have specific medical conditions or are taking other medications which could cause QT prolongation. Before utilizing imipramine, tell your doctor or pharmacist of all the drugs you take and in the event that you have actually some of the following conditions: certain heart problems (heart failure, sluggish heartbeat, QT prolongation in the EKG), genealogy of particular heart related illnesses (QT prolongation in the EKG, unexpected cardiac death).

Low levels of potassium or magnesium within the bloodstream may increase your risk also of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Speak to your doctor about using imipramine properly.

Before having surgery, tell your dentist or doctor that you are taking this medication.

This drug can make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit beverages that are alcoholic.

To decrease dizziness and lightheadedness, get up slowly whenever rising from a seated or lying position.

This drug might make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outside.

If you have diabetes, this drug may make it harder to control your blood sugar levels. Check your blood sugar regularly as directed by your doctor. Tell your doctor right away if you have symptoms such as increased thirst/urination, shakiness, unusual sweating, or hunger. Your anti-diabetic medication or diet could need to be adjusted.

Older adults may become more responsive to the adverse effects of this medication, especially dizziness (more likely when standing up), drowsiness, constipation, trouble urinating, mental/mood changes (such as confusion, agitation) and heart effects such as QT prolongation (see above). Dizziness, drowsiness, and confusion can raise the danger of falling.

Care is recommended when working with this medication in children. (See also the Warning section.)

This medication is used only when obviously needed during pregnancy. Infants created to mothers who took similar medicines during pregnancy may have signs such as trouble urinating, prolonged sleepiness, shaking, and seizures. Talk about the risks and benefits with your doctor.

Since untreated mental/mood dilemmas (such as depression, anxiety, panic disorders) can be a condition that is serious do not stop taking this medication unless directed by your doctor. You may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy if you are planning pregnancy, become pregnant, or think.

This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your physician before breast-feeding.

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