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This medication is used alone or with other medications to stop nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It really works by blocking one of the body's normal substances (serotonin) that causes nausea.

How to make use of Zofran

To prevent nausea from chemotherapy, take this medication by lips usually within half an hour before treatment begins. To avoid nausea from radiation treatment, take this medication by lips one to two hours prior to the begin of your therapy. To prevent nausea after surgery, take ondansetron by mouth an hour before the beginning of surgery. This medicine might be taken with or without food. However, your doctor may let you know not to ever consume before chemotherapy, radiation, or surgery.

If you are using the fluid type of this medication, use a measuring that is special or device to measure out your prescribed dose. Do not use a household spoon because you may not get the correct dose.

Take any other doses as directed by your doctor. Ondansetron could be taken on to 3 times a for 1 to 2 days after your chemotherapy or radiation treatment is finished day. It regularly in order to get the most benefit from it if you are taking this medication on a prescribed schedule, take. To help you remember, take it at the same times each day.

Dosage relies on your medical condition and response to therapy. The dosage for children may be based on also age and weight. The usual dose that is maximum patients with severe liver problems is 8 milligrams in 24 hours. Take this medication exactly as directed. Do not take more medication or take it more often than recommended. Ask your pharmacist or doctor if you have concerns.

Inform your doctor if your condition does not improve or if it worsens.

Side Impacts

Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation might occur. If these effects persist or worsen, notify your doctor promptly.

Keep in mind that your medical practitioner has prescribed this medication she has judged that the benefit to you is greater than the risk of adverse effects because he or. Many people using this medication do not have serious adverse effects.

Tell your doctor right away if any of the unlikely but severe side-effects occur: stomach pain, muscle tissue spasm/stiffness, vision modifications (e.g., temporary loss in eyesight, blurred vision).

Get medical help right away if some of these uncommon but very serious side effects occur: chest pain, slow/fast/irregular heartbeat, severe dizziness, fainting.

This medication may increase serotonin and seldom cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some associated with the following symptoms: fast heartbeat, hallucinations, lack of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

an extremely serious allergic reaction to this drug is unlikely, but stop taking this medication and seek immediate medical attention if it occurs. Symptoms of a serious reaction that is allergic: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

That is not a complete list of possible adverse effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about negative effects. You may report side effects to FDA at 1-800-FDA-1088 or at

In Canada - Call your physician for medical advice about part impacts. You may report effects that are side Health Canada at 1-866-234-2345.


Before taking ondansetron, tell your doctor or pharmacist if you have any other allergies if you are allergic to it; or to other serotonin blockers (e.g., granisetron); or. This product may contain ingredients that are inactive which can cause allergic reactions or other problems. Talk to your pharmacist for additional information.

Before using this medication, tell your medical professional or pharmacist your medical history, specially of: irregular heartbeat, liver condition, stomach/intestinal dilemmas (e.g., current abdominal surgery, ileus, swelling).

Ondansetron may cause a disorder that affects the heart rhythm (QT prolongation). QT prolongation can seldom cause severe (rarely fatal) fast/irregular heartbeat and other signs (such as for example severe dizziness, fainting) that require medical attention right away.

The chance of QT prolongation can be increased if you have certain medical conditions or are using other drugs which will cause QT prolongation. Before using ondansetron, tell your physician or pharmacist of all of the drugs you take and if you have any of the next conditions: certain heart disease (heart failure, sluggish heartbeat, QT prolongation into the EKG), family history of specific heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium into the bloodstream may increase your risk also of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Speak to your doctor about using ondansetron safely.

This drug might make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

To reduce dizziness and lightheadedness, get fully up slowly whenever increasing from a sitting or lying position.

Older adults may be more sensitive to the side effects of this medication, especially QT prolongation (see above).

This medication ought to be used only if clearly required during maternity. Discuss the risks and benefits along with your doctor.

It's not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

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